Protease activity degrades joint tissues after injury, causing arthritis progression over time. A new imaging technology allows us to visualize protease activity in real-time in the knee joints of living mice. We see increased joint degradation within 1 day of an ACL tear. This is long before any cartilage damage …
Our recent article published in Arthritis Research & Therapy examines this question. We used our mouse model of PTOA that relies on ACL-rupture to create a joint injury, and examined changes in subchondral bone, osteophyte formation, cartilage degradation using the …
It’s great to see that PubMed now indexes some of the manuscripts published in the ICRS journal “Cartilage”. This will definitely help increase the impact of the journal and the visibility of the manuscripts!
Elsevier publishing gives an insightful look into how recent publications are being received from their ‘article usage dashboard’, click here to see. A screenshot is below.
Our proteomics paper was accepted for publication in BBRC, and will serve as a reference documenting our method for the removal of high-abundance proteins from rodent plasma. This is an important first step that enables the quantification and study of lower-abundance …