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Publications

2018

  1. Inhibition of Early Response Genes Prevents Changes in Global Joint Metabolomic Profiles in Mouse Post-Traumatic Osteoarthritis. Haudenschild DR, Carlson AK, Zignego DL, Yik JHN, Hilmer JK, and June RK. Osteoarthritis & Cartilage. [Epub ahead of print] 18 December 2018
  2. Label-Free and Direct Visualization of Multivalent Binding of Bone Morphogenetic Protein-2 with Cartilage Oligomeric Matrix Protein. Tran V, Karsai A, Fong MC, Cai W, Yik JHN, Klineberg EO, Haudenschild DR, and Liu GY. Journal of Physical Chemistry.DOI: 10.1021/acs.jpcb.8b08564 Dec 15, 2018
  3. Effects of Micronized Cartilage Matrix on Cartilage Repair in Osteochondral Lesions of the Talus. Shieh AK, Singh SG, Nathe C, Lian E, Haudenschild DR, Nolta JA, Lee CA, Giza E, Kreulen CD. Cartilage. [Epub ahead of print] 29 August 2018
  4. Flavopiridol protects bone tissue by attenuating RANKL-induced osteoclast formation. Hu Z, Chen Y, Song L, Yik JHN, Haudenschild DR, and Shunwu Fan. Front. Pharmacol. 15 Feb 2018

2017

  1. Ca2+-Dependent Regulation of NFATc1 via KCa3.1 in Inflammatory Osteoclastogenesis. Grössinger EM, Kang M, Bouchareychas L, Sarin R, Haudenschild DR, Borodinsky LN, and Adamopoulos IE. The Journal of Immunology Dec 15, 2017
  2. Stem Cells in Spinal Fusion. Robbins MA, Haudenschild DR, Wegner AM, and Klineberg EO. Global Spine J. 2017; Vol 8: pg 801-810.

2016

  1. Inhibition of CDK9 prevents mechanical injury-induced inflammation, apoptosis and matrix degradation in cartilage explants. Hu Z, Yik JHN, Cissell DD, Michelier PV, Athanasiou KA, and Haudenschild DR. European Cells & Materials. 2016; Vol 30: pg 200-209.
  2. Binding to COMP Reduces the BMP2 Dose for Spinal Fusion in a Rat Model. Refaat M, Klineberg EO, Fong MC, Garcia TC, Leach JK, Haudenschild DR. Spine. Spine (Phila Pa 1976). 2016 Jul 15;41(14):E829-36

2015

  1. Articular Cartilage Injury and Potential Remedies. Chubinskaya S, Haudenschild DR, Gasser S, Stannard J, Krettek C, Borrelli J Jr. J Orthop Trauma 2015 Dec;29 Suppl 12:S47-52.
  2. Closed Joint ACL Disruption in Murine Model of PTA, Christiansen BA, Yik JHN, and Haudenschild DR. Chapter 7 in book “Post-Traumatic Arthritis: Pathogenesis, Diagnosis and Management”, edited by Steve Olson and Farshid Guilak. Published July.
  3. Non-Invasive Mouse Models of Post-Traumatic Osteoarthritis. Christiansen BA, Guilak F, Lockwood KA, Olson SA, Pitsillides AA, Sandell LJ, Silva MJ, van der Meulen MC, and Haudenschild DR. Osteoarthritis & Cartilage. 2015 Oct;23(10):1627-38.
  4. In-vitro and in-vivo imaging of MMP activity in cartilage and joint injury. Fukui T, Tenborg E, Yik JHN, and Haudenschild DR. Biochem Biophys Res Commun, 2015 May 8;460(3):741-6.
  5. Effect of Alendronate on Post-Traumatic Osteoarthritis Induced by Anterior Cruciate Ligament Rupture in Mice. Khorasani MS, Diko S, Hsia AW, Anderson MJ, Genetos DC, Haudenschild DR, and Christiansen BA. Arthritis Research & Therapy 2015, 17:30, Published 16 February.

2014

  1. High abundant protein removal from rodent blood for biomarker discovery. Haudenschild DR, Eldridge A, Lein PJ, and Chromy BA. Biochem Biophys Res Commun. Volume 455, Issues 1–2, 5 December 2014, Pages 84–89
  2. The effect of noggin interference in a rabbit posterolateral spinal fusion model. Klineberg E, Haudenschild DR, Snow KD, Garitty S, Christiansen BA, Acharya C, Maitra S, Gupta MC. Eur Spine J. 2014 Nov;23(11):2385-92.
  3. In vivo fluorescence reflectance imaging of protease activity in a mouse model of post-traumatic osteoarthritis. Satkunananthan PB, Anderson MJ, De Jesus NM, Haudenschild DR, Ripplinger CM, Christiansen BA. Osteoarthritis Cartialge 2014 Oct:22(10):1461-9
  4. Cartilage Oligomeric Matrix Protein and its binding partners in the cartilage extracellular matrix: Interaction, regulation and role in chondrogenesis. Acharya C, Yik JHN, Van Dinh V, Di Cesare PE, and Haudenschild DR. Matrix Biol Jul;37:102-11
  5. Cyclin-Dependent Kinase 9 Inhibition Protects Cartilage from the Catabolic Effects of Pro-Inflammatory Cytokines. Yik JHN, Hu A, Kumari R, Christiansen BA, and Haudenschild DR. Arthritis Rheumatol. 2014 Jun;66(6):1537-46. This article was commented upon, read our the comment and our reply here.
  6. Comparison of loading rate-dependent injury modes in a murine model of post-traumatic osteoarthritis. Lockwood KA, Chu BT, Anderson MJ, Haudenschild DR, Christiansen BA. J Orthop Res. 2014 Jan;32(1):79-88.

2013

  1. The Oncogene LRF Stimulates Proliferation of Mesenchymal Stem Cells and Inhibits Their Chondrogenic Differentiation.  Yik JHN, Li H, Acharya C, Kumari R, Fierro F, Haudenschild DR, Nolta J, Di Cesare PE. Cartilage. 2013 Oct;4(4):329-338.
  2. Effect of age and cytoskeletal elements on the indentation-dependent mechanical properties of chondrocytes. Chahine NO, Blanchette C, Thomas CB, Lu J, Haudenschild DR, Loots GG. PLoS One. 2013 Apr 16;8(4):e61651.
  3. Cartilage oligomeric matrix protein enhances osteogenesis by directly binding and activating bone morphogenetic protein-2. Ishida K, Acharya C, Christiansen BA, Yik JH, DiCesare PE, Haudenschild DR. Bone. 2013 Jul;55(1):23-35.
  4. c-Maf Transcription Factor Regulates ADAMTS-12 Expression in Human Chondrogenic Cells. Hong E, Yik JHN, Amanatullah DF, Di Cesare PE, Haudenschild DR. Cartilage. 2013 Apr;4(2) 177-186.

2012

  1. Interactions between FGF21 and BMP-2 in osteogenesis. Ishida K, Haudenschild DR. Biochem Biophys Res Commun. 2013 Mar 22;432(4):677-82.2012
  2. The oncogene LRF is a survival factor in chondrosarcoma and contributes to tumor malignancy and drug resistance. Kumari R, Li H, Haudenschild DR, Fierro F, Carlson CS, Overn P, Gupta L, Gupta K, Nolta J, Yik JH, Di Cesare PE. Carcinogenesis. 2012 Nov;33(11):2076-83.
  3. Identification of a 3Kbp mechanoresponsive promoter region in the human cartilage oligomeric matrix protein gene. Amanatullah DF, Lu J, Hecht J, Posey K, Yik J, Di Cesare PE, Haudenschild DR. Tissue Eng Part A. 2012 Sep;18(17-18):1882-9.
  4. Musculoskeletal changes following non-invasive knee injury using a novel mouse model of post-traumatic osteoarthritis. Christiansen BA, Anderson MJ, Lee CA, Williams JC, Yik JH, Haudenschild DR. Osteoarthritis Cartilage. 2012 Jul;20(7):773-82.
  5. Chondrogenic potential and homogeneity of cell populations of donor and recipient cells in a fresh osteochondral allograft: a case report. Haudenschild DR, Hong E, Hatcher S, Jamali AA. J Bone Joint Surg Am. 2012 Feb 1;94(3):e17.

2011

  1. Enhanced activity of transforming growth factor B1 (TGF-B1) bound to cartilage oligomeric matrix protein. Haudenschild DR, Hong E, Yik JH, Chromy B, Mörgelin M, Snow KD, Acharya C, Takada Y, Di Cesare PE. J Biol Chem. 2011 Dec 16;286(50):43250-8.
  2. Comparative analysis with collagen type II distinguishes cartilage oligomeric matrix protein as a primary TGF?-responsive gene. Li H, Haudenschild DR, Posey KL, Hecht JT, Di Cesare PE, Yik JH. Osteoarthritis Cartilage. 2011 Oct;19(10):1246-53.
  3. Role of c-Maf in Chondrocyte Differentiation: A Review.  Hong E, Di Cesare PE, Haudenschild DR. Cartilage. 2011 Jan;2(1):27-35.
  4. Vimentin contributes to changes in chondrocyte stiffness in osteoarthritis. Haudenschild DR, Chen J, Pang N, Steklov N, Grogan SP, Lotz MK, D’Lima DD. J Orthop Res. 2011 Jan;29(1):20-5.

2010 and older

  1. Rho kinase-dependent activation of SOX9 in chondrocytes. Haudenschild DR, Chen J, Pang N, Lotz MK, D’Lima DD. Arthritis Rheum. 2010 Jan;62(1):191-200.
  2. Characterization of the chondrocyte actin cytoskeleton in living three-dimensional culture: response to anabolic and catabolic stimuli. Haudenschild DR, Chen J, Steklov N, Lotz MK, D’Lima DD.Mol Cell Biomech. 2009 Sep;6(3):135-44.
  3. Rho kinase-dependent CCL20 induced by dynamic compression of human chondrocytes. Haudenschild DR, Nguyen B, Chen J, D’Lima DD, Lotz MK. Arthritis Rheum. 2008 Sep;58(9):2735-42.
  4. Immunolocalization of IL-17A, IL-17B, and their receptors in chondrocytes during fracture healing. Kokubu T, Haudenschild DR, Moseley TA, Rose L, Reddi AH. J Histochem Cytochem. 2008 Feb;56(2):89-95.
  5. Dynamic compression of chondrocytes induces a Rho kinase-dependent reorganization of the actin cytoskeleton. Haudenschild DR, D’Lima DD, Lotz MK. Biorheology. 2008;45(3-4):219-28.
  6. Generation of interleukin-17 receptor-like protein (IL-17RL) in prostate by alternative splicing of RNA. Haudenschild DR, Curtiss SB, Moseley TA, Reddi AH. Prostate. 2006 Sep 1;66(12):1268-74.
  7. Bone morphogenetic protein (BMP)-6 signaling and BMP antagonist noggin in prostate cancer. Haudenschild DR, Palmer SM, Moseley TA, You Z, Reddi AH. Cancer Res. 2004 Nov 15;64(22):8276-84.
  8. Interleukin-17 family and IL-17 receptors. Moseley TA, Haudenschild DR, Rose L, Reddi AH. Cytokine Growth Factor Rev. 2003 Apr;14(2):155-74. Review.
  9. Differential expression of multiple genes during articular chondrocyte redifferentiation. Haudenschild DR, McPherson JM, Tubo R, Binette F. Anat Rec. 2001 May 1;263(1):91-8.
  10. Expression of a stable articular cartilage phenotype without evidence of hypertrophy by adult human articular chondrocytes in vitro. Binette F, McQuaid DP, Haudenschild DR, Yaeger PC, McPherson JM, Tubo R. J Orthop Res. 1998 Mar;16(2):207-16.
  11. Cartilage matrix protein: expression patterns in chicken, mouse, and human. Chen Q, Johnson DM, Haudenschild DR, Goetinck PF. Ann N Y Acad Sci. 1996 Jun 8;785:238-40.
  12. Cartilage matrix protein forms a type II collagen-independent filamentous network: analysis in primary cell cultures with a retrovirus expression system. Chen Q, Johnson DM, Haudenschild DR, Tondravi MM, Goetinck PF. Mol Biol Cell. 1995 Dec;6(12):1743-53.
  13. Progression and recapitulation of the chondrocyte differentiation program: cartilage matrix protein is a marker for cartilage maturation. Chen Q, Johnson DM, Haudenschild DR, Goetinck PF. Dev Biol. 1995 Nov;172(1):293-306.
  14. The role of coiled-coil alpha-helices and disulfide bonds in the assembly and stabilization of cartilage matrix protein subunits. A mutational analysis. Haudenschild DR, Tondravi MM, Hofer U, Chen Q, Goetinck PF. J Biol Chem. 1995 Sep 29;270(39):23150-4.
  15. Link protein is ubiquitously expressed in non-cartilaginous tissues where it enhances and stabilizes the interaction of proteoglycans with hyaluronic acid. Binette F, Cravens J, Kahoussi B, Haudenschild DR, Goetinck PF. J Biol Chem. 1994 Jul 22;269(29):19116-22.
  16. Cartilage matrix protein binds to collagen and plays a role in collagen fibrillogenesis. Tondravi MM, Winterbottom N, Haudenschild DR, Goetinck PF. Prog Clin Biol Res. 1993;383B:515-22.