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Category: Updates

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Discussion on Cdk9 Inhibitor in Cartilage

By dhaudi Posted on October 2, 2014 Posted in Blog, Uncategorized, Updates
Discussion on Cdk9 Inhibitor in Cartilage

A very interesting letter was published regarding our Arthritis & Rheumatology manuscript where we show that Cdk9 inhibition protects cartilage from the catabolic effects of pro-inflammatory cytokines. The full letter, and our reply, will be published in an upcoming issue …

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COMP “Interactome” Review in Matrix Biology

By dhaudi Posted on July 7, 2014 Posted in Blog, Uncategorized, Updates
COMP “Interactome” Review in Matrix Biology

Chitra Acharya’s review of the COMP-interacting proteins and matrix components was just published – Congratulations! Abstract Thrombospondins (TSPs) are widely known as a family of five calcium-binding matricellular proteins. While these proteins belong to the same family, they are encoded …

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OTA, OREF, CTSC Fellowship Grants

By dhaudi Posted on June 17, 2014 Posted in Blog, Uncategorized, Updates
OTA, OREF, CTSC Fellowship Grants

Congratulations to orthopaedic research resident Adam Wegner for obtaining research funding from the Orthopaedic Trauma Association (OTA) and the Orthopaedic Research and Education Foundation (OREF) for his studies on how the production of reactive oxygen species affects post-traumatic osteoarthritis.  Congratulations to …

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Noggin in Spinal Fusion – published in Eur. Spine J.

By dhaudi Posted on May 14, 2014 Posted in Blog, Uncategorized, Updates
Noggin in Spinal Fusion – published in Eur. Spine J.
European Spine Journal Logo

This study was finally published – we ask whether we could augment BMP activity by reducing the BMP antagonists in spinal fusion surgeries in a rabbit model. Abstract (pubmed link) STUDY DESIGN: Noggin protein levels and spinal fusion rates were …

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Protection of Cartilage from Cytokines – published in A&R

By dhaudi Posted on January 29, 2014 Posted in Blog, Uncategorized, Updates
Protection of Cartilage from Cytokines – published in A&R

Congratulations to our team for getting this story published in the top rheumatology journal! We take a new approach to protect cartilage from inflammatory cytokines by targeting a critical transcriptional checkpoint common to all primary response genes. Abstract (pubmed link) …

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